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Hacking Darwin: Genetic Engineering and the Future of Humanity
by Jamie Metzl

Language

English

Pages

352

Publication Date

April 23, 2019

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Customer Reviews
<p>"A gifted and thoughtful writer, Metzl brings us to the frontiers of biology and technology, and reveals a world full of promise and peril." — Siddhartha Mukherjee MD, <em>New York Times </em>bestselling author of <em>The Emperor of All Maladies</em> and<em> The Gene</em></p><p><strong>Passionate, provocative, and highly illuminating, <em>Hacking Darwin </em>is the must read book about the future of our species for fans of <em>Homo Deus</em> and <em>The Gene</em>. </strong></p><p><em>After 3.8 billion years humankind is about to start evolving by new rules...</em></p><p>From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives — sex, war, love, and death. </p><p>At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race. </p><p> Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we? <br /></p>
Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fou...
by CRC Press

Language

English

Pages

1337

Publication Date

January 20, 2015

Product Description
Customer Reviews
<P><EM>The Most Comprehensive, State-of-the-Art Book on Using Gene and Cell Therapy in Clinical Medicine</EM></P><br /><P><STRONG>Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition</STRONG> presents extensive background and basic information, state-of-the-art technologies, important achievements, and lingering challenges in the fields of gene and cell therapies. The fourth edition of this bestseller continues to provide the most comprehensive coverage of these fields in one volume. Some chapters have expanded introductions, making the book even more suitable for classroom use. This edition also offers more material on the contributors’ research efforts as well as current technologies, disease targets, and clinical applications.</P><br /><P></P><br /><P>Divided into four sections, the book covers:</P><br /><UL><br /><LI>Delivery systems and therapeutic strategies</LI><br /><LI>Other therapeutic strategies, including technologies that knock down gene expression</LI><br /><LI>Gene expression, regulation, and detection</LI><br /><LI>Gene and cell therapies, disease targets, clinical trials, and regulatory issues</LI></UL><br /><P></P><br /><P>Accessible to a broad audience, including students, scientists, physicians, and lay people, this book provides readers with up-to-date, interdisciplinary knowledge and tools to tackle the evolving areas of gene therapy, cell therapy, and tissue engineering. From introductory information to state-of-the-art technologies and concepts, the book helps readers understand vector design and construction, delivery systems, therapeutic strategies, gene expression and detection, disease targets, clinical applications and trials, cell-based therapies, novel imaging systems, gene regulation, and regulatory affairs. </P>
Blueprint: The Evolutionary Origins of a Good Society
by Nicholas A. Christakis

Language

English

Pages

442

Publication Date

March 26, 2019

Product Description
Customer Reviews
<b>"A dazzlingly erudite synthesis of history, philosophy, anthropology, genetics, sociology, economics, epidemiology, statistics, and more" (Frank Bruni, <i>New York Times</i>), <i>Blueprint</i> shows how and why evolution has placed us on a humane path -- and how we are united by our common humanity. </b><br /><br /><div>For too long, scientists have focused on the dark side of our biological heritage: our capacity for aggression, cruelty, prejudice, and self-interest. But natural selection has given us a suite of beneficial social features, including our capacity for love, friendship, cooperation, and learning. Beneath all our inventions -- our tools, farms, machines, cities, nations -- we carry with us innate proclivities to make a good society. </div><div><br /></div><div>In <i>Blueprint</i>, Nicholas A. Christakis introduces the compelling idea that our genes affect not only our bodies and behaviors, but also the ways in which we make societies, ones that are surprisingly similar worldwide. </div><div><br /></div><div>With many vivid examples -- including diverse historical and contemporary cultures, communities formed in the wake of shipwrecks, commune dwellers seeking utopia, online groups thrown together by design or involving artificially intelligent bots, and even the tender and complex social arrangements of elephants and dolphins that so resemble our own -- Christakis shows that, despite a human history replete with violence, we cannot escape our social blueprint for goodness. </div><div><br /></div><div>In a world of increasing political and economic polarization, it's tempting to ignore the positive role of our evolutionary past. But by exploring the ancient roots of goodness in civilization, <i>Blueprint </i>shows that our genes have shaped societies for our welfare and that, in a feedback loop stretching back many thousands of years, societies have shaped, and are still shaping, our genes today. </div>
Seed Of Israel: DNA Guide To Tracing Your Jewish Ancestry
by Joshua Robbin Marks

Language

English

Pages

57

Publication Date

June 16, 2019

Product Description
Customer Reviews
Jews are an ethnoreligious group indigenous to the Land of Israel. The Jewish people were scattered across the world during multiple exiles. What does our DNA tell us about our journey from our ancestral homeland of Judah to Europe or North Africa or the Middle East? What does it mean when your DNA test comes back as Ashkenazi or Sephardic or Mizrahi? What admixture is underneath these categories? These profound questions relating to Jewish genetics are just beginning to be answered and some questions might never be answered. But modern genetic science has offered a window into the Jewish past that previous generations of Jews could have only dreamed of. This book is for anyone interested in finding out their Jewish ancestry and interpreting the results. This DNA journey can provide unexpected twists and turns and surprising results so get ready. Ultimately, as it did for me, it will hopefully strengthen your Jewish identity and your connection to Am Yisrael, People of Israel.
The Selfish Gene: 40th Anniversary edition (Oxford Landmark Scien...
by Richard Dawkins

Language

English

Pages

496

Publication Date

June 02, 2016

Product Description
Customer Reviews
The million copy international bestseller, critically acclaimed and translated into over 25 languages.<br /><br />As influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology<br />community, generating much debate and stimulating whole new areas of research. Forty years later, its insights remain as relevant today as on the day it was published.<br /><br />This 40th anniversary edition includes a new epilogue from the author discussing the continuing relevance of these ideas in evolutionary biology today, as well as the original prefaces and foreword, and extracts from early reviews.<br /><br />Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.
Who We Are and How We Got Here: Ancient DNA and the New Science o...
by David Reich

Language

English

Pages

368

Publication Date

March 27, 2018

Product Description
Customer Reviews
<b>A groundbreaking book about how ancient DNA has profoundly changed our understanding of human history.</b><br /> <br />Geneticists like David Reich have made astounding advances in the field of genomics, which is proving to be as important as archeology, linguistics, and written records as a means to understand our ancestry. <br /> <br />In <i>Who We Are and How We Got Here</i>, Reich allows readers to discover how the human genome provides not only all the information a human embryo needs to develop but also the hidden story of our species. Reich delves into how the genomic revolution is transforming our understanding of modern humans and how DNA studies reveal deep inequalities among different populations, between the sexes, and among individuals. Provocatively, Reich’s book suggests that there might very well be biological differences among human populations but that these differences are unlikely to conform to common stereotypes.<br /> <br />Drawing upon revolutionary findings and unparalleled scientific studies, <i>Who We Are and How We Got Here</i> is a captivating glimpse into humankind—where we came from and what that says about our lives today.
The Guarded Gate: Bigotry, Eugenics and the Law That Kept Two Gen...
by Daniel Okrent

Language

English

Pages

497

Publication Date

May 07, 2019

Product Description
Customer Reviews
<b>By the widely celebrated <i>New York Times</i> bestselling author of <i>Last Call</i>—the powerful, definitive, and timely account of how the rise of eugenics helped America close the immigration door to “inferiors” in the 1920s.</b><BR><BR>A forgotten, dark chapter of American history with implications for the current day, <i>The Guarded Gate </i>tells the story of the scientists who argued that certain nationalities were inherently inferior, providing the intellectual justification for the harshest immigration law in American history. Brandished by the upper class Bostonians and New Yorkers—many of them progressives—who led the anti-immigration movement, the eugenic arguments helped keep hundreds of thousands of Jews, Italians, and other unwanted groups out of the US for more than 40 years.<BR> <BR>Over five years in the writing, <i>The Guarded Gate </i>tells the complete story from its beginning in 1895, when Henry Cabot Lodge and other Boston Brahmins launched their anti-immigrant campaign. In 1921, Vice President Calvin Coolidge declared that “biological laws” had proven the inferiority of southern and eastern Europeans; the restrictive law was enacted three years later. In his characteristic style, both lively and authoritative, Okrent brings to life the rich cast of characters from this time, including Lodge’s closest friend, Theodore Roosevelt; Charles Darwin’s first cousin, Francis Galton, the idiosyncratic polymath who gave life to eugenics; the fabulously wealthy and profoundly bigoted Madison Grant, founder of the Bronx Zoo, and his best friend, H. Fairfield Osborn, director of the American Museum of Natural History; Margaret Sanger, who saw eugenics as a sensible adjunct to her birth control campaign; and Maxwell Perkins, the celebrated editor of Hemingway and Fitzgerald. A work of history relevant for today, <i>The Guarded Gate</i> is an important, insightful tale that painstakingly connects the American eugenicists to the rise of Nazism, and shows how their beliefs found fertile soil in the minds of citizens and leaders both here and abroad.
Advanced Genetic Genealogy: Techniques and Case Studies
by Debbie Parker Wayne

Language

English

Pages

717

Publication Date

June 13, 2019

Product Description
Customer Reviews
Advanced Genetic Genealogy: Techniques and Case Studies helps intermediate researchers move up to the next level and advanced researchers apply the new DNA standards and write about DNA. This new book offers an in-home course in advanced genetic genealogy. Case studies demonstrate analyzing the DNA test results, correlating with documentary evidence, and writing about the findings, all incorporating the updated standards for using DNA. Full-color illustrations help the genealogist incorporate these techniques into personal or client research projects. Each of the fourteen chapters was written by a professional genealogist with DNA experience.<br /><br />Eight chapters study real families (some using anonymized identities), including methods, tools, and techniques. Jim Bartlett covers how to triangulate a genome (mapping DNA segments to ancestors). Blaine T. Bettinger demonstrates the methodology for visual phasing (mapping DNA segments to the grandparents who passed down the segment to descendants, even when the grandparents cannot be tested). Kathryn J. Johnston shows how to use X-DNA to identify and confirm ancestral lines. James M. Owston describes findings of the Owston Y-DNA project. Melissa A. Johnson covers adoption and misattributed parentage research. Kimberly T. Powell provides guidance when researching families with endogamy and pedigree collapse. Debbie Parker Wayne combines atDNA and Y-DNA in a Parker family study. Ann Turner describes the raw DNA data and lab processes.<br /><br />Three middle chapters cover genealogy standards as they relate to DNA and documentary evidence. Karen Stanbary applies the Genealogical Proof Standard to genetic genealogy in a hypothetical unknown parentage case illustrating start-to-finish analysis. Patricia Lee Hobbs uses atDNA to identify an unknown ancestor and that ancestor's maiden name, moving back and forth between documentary and DNA evidence. Thomas W. Jones describes best practices for genealogical writing and publishing when incorporating DNA evidence.<br /><br />Three concluding chapters deal with ethics, emotions, and the future. Judy G. Russell covers ethical considerations. Michael D. Lacopo describes the effect on relationships when family secrets are uncovered, surfacing issues for all concerned. Debbie Kennett covers the current limitations and future promise of using DNA for genealogy. An extensive glossary, list of recommended resources, and index are included.
Dr. Gundry's Diet Evolution: Turn Off the Genes That Are Killing ...
by Dr. Steven R. Gundry

Language

English

Pages

304

Publication Date

March 11, 2008

Product Description
Customer Reviews
"Dr. Gundry has crafted a wise program with a powerful track record.” <br />–Mehmet Oz, M.D.<br /><br />Does losing weight and staying healthy feel like a battle? Well, it’s really a war. Your enemies are your own genes, backed by millions of years of evolution, and the only way to win is to outsmart them. Renowned surgeon and founder of Gundry MD, Dr. Steven Gundry’s revolutionary book shares the health secrets other doctors won’t tell you:<br /><br />• Why plants are “good” for you because they’re “bad” for you, and meat is “bad” because it’s “good” for you<br />• Why plateauing on this diet is actually a sign that you’re on the right track<br />• Why artificial sweeteners have the same effects as sugar on your health and your waistline<br />• Why taking antacids, statins, and drugs for high blood pressure and arthritis masks health issues instead of addressing them<br /><br />Along with the meal planner, 70 delicious recipes, and inspirational stories, Dr. Gundry’s easy-to-memorize tips will keep you healthy and on course.
The Tangled Tree: A Radical New History of Life
by David Quammen

Language

English

Pages

480

Publication Date

August 14, 2018

Product Description
Customer Reviews
<b>Longlisted for the National Book Award for Nonfiction and A <i>New York Times</i> Notable Book of 2018</b><BR> <BR> <b>Nonpareil science writer David Quammen explains how recent discoveries in molecular biology can change our understanding of evolution and life’s history, with powerful implications for human health and even our own human nature. </b><BR><BR>In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.<BR> <BR> In <i>The </i><i>Tangled Tree</i> David Quammen, “one of that rare breed of science journalists who blends exploration with a talent for synthesis and storytelling” (<i>Nature</i>), chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.<BR> <BR> “Quammen is no ordinary writer. He is simply astonishing, one of that rare class of writer gifted with verve, ingenuity, humor, guts, and great heart” (<i>Elle</i>). Now, in <i>The Tangled Tree</i>, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies such as CRISPR, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. <i>The Tangled Tree </i>is a brilliant guide to our transformed understanding of evolution, of life’s history, and of our own human nature.

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