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The Immortal Life of Henrietta Lacks
by Rebecca Skloot

Language

English

Pages

393

Publication Date

January 28, 2010

Product Description
Customer Reviews
<b><b>Now an HBO® Film starring Oprah Winfrey and Rose Byrne</b><br /><br />#1 NEW YORK TIMES BESTSELLER<br /></b><br />Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor black tobacco farmer whose cells—taken without her knowledge in 1951—became one of the most important tools in medicine, vital for developing the polio vaccine, cloning, gene mapping, and more. Henrietta's cells have been bought and sold by the billions, yet she remains virtually unknown, and her family can't afford health insurance. This phenomenal New York Times bestseller tells a riveting story of the collision between ethics, race, and medicine; of scientific discovery and faith healing; and of a daughter consumed with questions about the mother she never knew.
Deep Medicine: How Artificial Intelligence Can Make Healthcare Hu...
by Eric Topol

Language

English

Pages

341

Publication Date

March 12, 2019

Product Description
Customer Reviews
<div><b>One of America's top doctors reveals how AI will empower physicians and revolutionize patient care </b></div> <div><br /></div> <div>Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In <i>Deep Medicine</i>, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard.</div> <div><br /></div> <div>Innovative, provocative, and hopeful, <i>Deep Medicine</i> shows us how the awesome power of AI can make medicine better, for all the humans involved.</div>
The Book of Why: The New Science of Cause and Effect
by , Dana Mackenzie

Language

English

Pages

423

Publication Date

May 15, 2018

Product Description
Customer Reviews
<div><b>A Turing Award-winning computer scientist and statistician shows how understanding causality has revolutionized science and will revolutionize artificial intelligence</b></div><div><b><br /></b></div><div>"Correlation is not causation." This mantra, chanted by scientists for more than a century, has led to a virtual prohibition on causal talk. Today, that taboo is dead. The causal revolution, instigated by Judea Pearl and his colleagues, has cut through a century of confusion and established causality--the study of cause and effect--on a firm scientific basis. His work explains how we can know easy things, like whether it was rain or a sprinkler that made a sidewalk wet; and how to answer hard questions, like whether a drug cured an illness. Pearl's work enables us to know not just whether one thing causes another: it lets us explore the world that is and the worlds that could have been. It shows us the essence of human thought and key to artificial intelligence. Anyone who wants to understand either needs <i>The Book of Why</i>.<br /><br /></div><div><br /></div>
The Model Thinker: What You Need to Know to Make Data Work for Yo...
by Scott E. Page

Language

English

Pages

398

Publication Date

November 27, 2018

Product Description
Customer Reviews
<div><b>How anyone can become a data ninja</b><br /><br /> From the stock market to genomics laboratories, census figures to marketing email blasts, we are awash with data. But as anyone who has ever opened up a spreadsheet packed with seemingly infinite lines of data knows, numbers aren't enough: we need to know how to make those numbers talk. In <i>The Model Thinker</i>, social scientist Scott E. Page shows us the mathematical, statistical, and computational models--from linear regression to random walks and far beyond--that can turn anyone into a genius. At the core of the book is Page's "many-model paradigm," which shows the reader how to apply multiple models to organize the data, leading to wiser choices, more accurate predictions, and more robust designs. <i>The Model Thinker </i>provides a toolkit for business people, students, scientists, pollsters, and bloggers to make them better, clearer thinkers, able to leverage data and information to their advantage.<br /><br /></div>
Tweak: Growing Up on Methamphetamines
by Nic Sheff

Language

English

Pages

340

Publication Date

April 24, 2009

Product Description
Customer Reviews
<b>The story that inspired the major motion picture <i>Beautiful Boy</i> featuring Steve Carell and Timothée Chalamet<i>.</i></b><BR> <BR><b>This <i>New York Times </i>bestselling memoir of a young man’s addiction to methamphetamine tells a raw, harrowing, and ultimately hopeful tale of the road from relapse to recovery.</b><BR><BR>Nic Sheff was drunk for the first time at age eleven. In the years that followed, he would regularly smoke pot, do cocaine and Ecstasy, and develop addictions to crystal meth and heroin. Even so, he felt like he would always be able to quit and put his life together whenever he needed to. It took a violent relapse one summer in California to convince him otherwise. In a voice that is raw and honest, Nic spares no detail in telling us the compelling, heartbreaking, and true story of his relapse and the road to recovery. As we watch Nic plunge into the mental and physical depths of drug addiction, he paints a picture for us of a person at odds with his past, with his family, with his substances, and with himself. It's a harrowing portrait—but not one without hope.
Applied Surrogate Endpoint Evaluation Methods with SAS and R (Cha...
by , Wim Van der Elst

Language

English

Pages

396

Publication Date

November 30, 2016

Product Description
Customer Reviews
<P>An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.</P>
The Salt Fix: Why the Experts Got It All Wrong--and How Eating Mo...
by James DiNicolantonio

Language

English

Pages

274

Publication Date

June 06, 2017

Product Description
Customer Reviews
 We all know the dangers of sugar and salt: but the danger attributed to the second white crystal has more to do with getting too little of it, not too much. A leading cardiovascular research scientist and doctor of pharmacy overturns conventional thinking about salt and explores instead the little-understood importance of it, the health dangers of having too little, and how salt can actually help you improve sports performance, crush sugar cravings, and stave off common chronic illnesses.<br />   Too little salt in the diet can shift the body into semi-starvation mode and cause insulin resistance, and may even cause you to absorb twice as much fat for every gram you consume. Too little salt in certain populations can actually <i>increase</i> blood pressure, as well as resting heart rate. We need salt in order to hydrate and nourish our cells, transmit nerve signals, contract our muscles, ensure proper digestion and breathing, and maintain proper heart function. <i>The Salt Fix</i> will show how we wrongly demonized this essential micronutrient as well as explain what the current science really says about this misunderstood mineral and how to maximize its effect so you can enjoy ideal health and longevity.
Applied Predictive Modeling
by , Kjell Johnson

Language

English

Pages

600

Publication Date

May 17, 2013

Product Description
Customer Reviews
<b>Winner of the 2014 Technometrics Ziegel Prize for Outstanding Book</b><br /><br /><i>Applied Predictive Modeling</i> covers the overall predictive modeling process, beginning with the crucial steps of data preprocessing, data splitting and foundations of model tuning.  The text then provides intuitive explanations of numerous common and modern regression and classification techniques, always with an emphasis on illustrating and solving real data problems.  Addressing practical concerns extends beyond model fitting to topics such as handling class imbalance, selecting predictors, and pinpointing causes of poor model performance―all of which are problems that occur frequently in practice.<br /> <br />The text illustrates all parts of the modeling process through many hands-on, real-life examples.  And every chapter contains extensive R code for each step of the process.  The data sets and corresponding code are available in the book's companion AppliedPredictiveModeling R package, which is freely available on the CRAN archive.<br /> <br />This multi-purpose text can be used as an introduction to predictive models and the overall modeling process, a practitioner's reference handbook, or as a text for advanced undergraduate or graduate level predictive modeling courses.  To that end, each chapter contains problem sets to help solidify the covered concepts and uses data available in the book's R package.<br /> <br />Readers and students interested in implementing the methods should have some basic knowledge of R.  And a handful of the more advanced topics require some mathematical knowledge.</div>
Enabling Discovery, Development, and Translation of Treatments fo...
by , Engineering, and Medici...

Language

English

Pages

92

Publication Date

December 31, 1969

Product Description
Customer Reviews
<p>Major depressive disorder (MDD) is recognized worldwide as a major cause of disability, morbidity, and mortality. According to the World Health Organization, unipolar depressive disorders affect more than 150 million people around the world and represent the leading cause of years lost due to disability among both men and women. In the United States alone, nearly 8 percent of persons over the age of 12 report current depression. MDD has long been defined primarily as a mood disorder. However,more recently people have begun to recognize effects on cognition as a major contributor to the disablement that accompanies depression and to consider this an underrecognized treatment target for depression.</p> <p>To explore how best to enable the discovery, development, and translation of treatments for cognitive dysfunction in depression, including a focus on the regulatory path forward, the Institute of Medicine's Forum on Neuroscience and Nervous Disorders convened key stakeholders at a workshop in February 2015. This report summarizes the presentations from expert speakers and discussions among workshop participants.</p>
Superbugs: The Race to Stop an Epidemic
by Matt McCarthy

Language

English

Pages

304

Publication Date

May 21, 2019

Product Description
Customer Reviews
<b><b>"An amazing, informative book that changes our perspective on medicine, microbes and our future."</b><br /><b>--Siddhartha Mukherjee, MD, </b><b><i>New York Times</i></b><b> bestselling author of </b><b><i>The Emperor of All Maladies</i></b><b></b><br /><b></b><br /><b>A </b><b><i>New York Times</i></b><b> bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs.</b></b><br /><br />Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable <i>Superbugs</i>, and the results will impact nothing less than the future of humanity.<br /><br />Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more.<br /><br />The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?

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